ILF2 CLIA Kit for Human(Homo sapiens) | EIAab.comILF2 CLIA Kit for Human(Homo sapiens)

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Index > Protein center > ILF2(Gene name) > Human

ILF2 (Gene name),

Interleukin enhancer-binding factor 2 (Protein name ), ILF2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ILF2(PRO3063;NF45);

Protein name:

Interleukin enhancer-binding factor 2;

Alternative:

Nuclear factor of activated T-cells 45 kDa;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Forms heterodimers with ILF3. ILF2-ILF3 heterodimers may also bind to PRKDC/XRCC7: this may stabilize the interaction of PRKDC/XRCC7 and the heterodimeric complex of G22P1/KU70 and XRCC5/KU80. Forms a complex with ILF3, YLPM1, KHDRBS1, RBMX, NCOA5 and PPP1CA. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1.

Function:

Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.

Subcellular Location:

Nucleus nucleolus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Protein Attributes:

Sequence length:

390

Sequence:

50:

100:

150:

200:

250:

300:

350:

390:

VTPSEKAYEK | PPEKKEGEEE | EENTEEPPQG | EEEESMETQE |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q12905

UniGene:

Hs.75117

MIM:

603181

KEGG:

hsa:3608

String:

Q12905

Pfam:

PF07528

STRING:

9606.ENSP00000355011

Uniprot:

Q12905

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ELISA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

E15394h

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96T

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ELISA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

E15394m

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96T

ELISA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

E15394r

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96T

CLIA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

U15394m

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Packing:

96T

CLIA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

U15394h

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MSDS:

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Packing:

96T

CLIA Kit for Human Interleukin enhancer-binding factor 2

Cat.:

U15394r

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96T

Polyclonal Antibody for Human Interleukin enhancer-binding factor 2

Cat.:

P15394Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Interleukin enhancer-binding factor 2

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P15394Rb-h

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Polyclonal Antibody for Human Interleukin enhancer-binding factor 2

Cat.:

P15394Rb-m

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Packing:

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Monoclonal Antibody for Human Interleukin enhancer-binding factor 2

Protein for Human Interleukin enhancer-binding factor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90."
Kao P.N. , Chen L. , Brock G. , Ng J. , Kenny J. , Smith A.J. , Corthesy B.
J. Biol. Chem.269:20691-20699(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];PROTEIN SEQUENCE OF 62-75; 82-102 AND 330-343;SUBCELLULAR LOCATION
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thymus.
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
6.

"Functional prediction of the coding sequences of 32 new genes deduced by analysis of cDNA clones from human fetal liver."
Zhang C. , Yu Y. , Zhang S. , Ouyang S. , Luo L. , Wei H. , Zhou G. , Zhou W. , Bi J. , Zhang Y. , Liu M. , He F.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 157-390
tissue: Fetal liver.
7.

"DNA-dependent protein kinase interacts with antigen receptor response element binding proteins NF90 and NF45."
Ting N.S.Y. , Kao P.N. , Chan D.W. , Lintott L.G. , Lees-Miller S.P.
J. Biol. Chem.273:2136-2145(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH G22P1; PRKDC AND XRCC5
8.

"Autoantibodies define a family of proteins with conserved double-stranded RNA-binding domains as well as DNA binding activity."
Satoh M. , Shaheen V.M. , Kao P.N. , Okano T. , Shaw M. , Yoshida H. , Richards H.B. , Reeves W.H.
J. Biol. Chem.274:34598-34604(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ILF3
9.

"Directed proteomic analysis of the human nucleolus."
Andersen J.S. , Lyon C.E. , Fox A.H. , Leung A.K.L. , Lam Y.W. , Steen H. , Mann M. , Lamond A.I.
Curr. Biol.12:1-11(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
10.

"Functional proteomic analysis of human nucleolus."
Scherl A. , Coute Y. , Deon C. , Calle A. , Kindbeiter K. , Sanchez J.-C. , Greco A. , Hochstrasser D.F. , Diaz J.-J.
Mol. Biol. Cell13:4100-4109(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"The RNA binding protein nuclear factor 90 functions as both a positive and negative regulator of gene expression in mammalian cells."
Reichman T.W. , Muniz L.C. , Mathews M.B.
Mol. Cell. Biol.22:343-356(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH ILF3
12.

"The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G."
Ulke-Lemee A. , Trinkle-Mulcahy L. , Chaulk S. , Bernstein N.K. , Morrice N. , Glover M. , Lamond A.I. , Moorhead G.B.G.
Biochim. Biophys. Acta1774:1339-1350(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH ILF3; YLPM1; KHDRBS1; RBMX; NCOA5 AND PPP1CA
13.

"Molecular composition of IMP1 ribonucleoprotein granules."
Joeson L. , Vikesaa J. , Krogh A. , Nielsen L.K. , Hansen T. , Borup R. , Johnsen A.H. , Christiansen J. , Nielsen F.C.
Mol. Cell. Proteomics6:798-811(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A MRNP GRANULE COMPLEX;INTERACTION WITH IGF2BP1;SUBCELLULAR LOCATION
14.

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-388;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
15.

"Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense."
Harashima A. , Guettouche T. , Barber G.N.
Genes Dev.24:2640-2653(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
16.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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